Salmon Nasal Cartilage Proteoglycan
サケ鼻軟骨プロテオグリカン (Sake Bi-Nankotsu Proteoglycan)

Why source from Japan
Proteoglycan extracted from salmon nasal cartilage, developed at Hirosaki University in Aomori Prefecture.
Key spec
INCI Proteoglycan; FFC notification(s) on file; MOQ from 100 g – 10 kg.
Typical end-product
Premium serums and essences — High-end moisturizing and skin elasticity, often paired with hyaluronic acid and ceramides.
At a glance
- Suppliers listed
- 6 suppliers
- Typical MOQ
- 100 g – 10 kg
- Typical lead time
- 4-8 weeks
- Regions of origin
- Aomori Prefecture
- Category
- Cosmetic raw materials
- Harvest season
- Salmon season (Autumn-Winter)
- Price range
- TBD
- Japan regulatory status
- PMDA approved for cosmetics; FFC-accepted for joint comfort and skin elasticity
- INCI name
- Proteoglycan
- Japanese name
- サケ鼻軟骨プロテオグリカン
- Romaji
- Sake Bi-Nankotsu Proteoglycan
About this ingredient
Proteoglycan extracted from salmon nasal cartilage, developed at Hirosaki University in Aomori Prefecture. Water-retention capacity approximately 1.3 times that of hyaluronic acid.
Regulatory status
| Japan | PMDA approved for cosmetics; FFC-accepted for joint comfort and skin elasticity |
|---|---|
| EU | CosIng listed (confirm current) |
| United States | Acceptable for cosmetics under MoCRA |
| China | Confirm IECIC listing |
FAQ for OEM buyers
Q. Where is salmon proteoglycan produced in Japan?
Production is centered in Aomori Prefecture, leveraging the local salmon supply chain.
Sources
- Source dossier (provided)
Industry-knowledge claim — not yet pinned to a single primary source
Q. What is the typical MOQ?
MOQs commonly range from 100 g (for cosmetic R&D quantities) to 10 kg (for production lots). Confirm the exact grade-specific MOQ with the supplier.
Sources
- Source dossier (provided)
Industry-knowledge claim — not yet pinned to a single primary source
Q. Are there seasonal supply considerations?
Raw cartilage availability follows the autumn-winter salmon season, but suppliers typically buffer inventory to provide year-round shipment of the finished extract.
Sources
- Source dossier (provided)
Industry-knowledge claim — not yet pinned to a single primary source
Q. Is this ingredient acceptable for cosmetic use in the United States?
Salmon cartilage proteoglycan is acceptable as a cosmetic ingredient in the US under MoCRA-era requirements. Importers should ensure facility registration and product listing as required.
Sources
Q. Is the ingredient listed in EU CosIng?
Industry references list the ingredient under CosIng for cosmetic use; buyers should verify the latest CosIng entry directly before label finalization.
Sources
Use cases
Premium serums and essences
- Positioning
- High-end moisturizing and skin elasticity, often paired with hyaluronic acid and ceramides
- Formulation notes
- Compatible with leave-on aqueous systems; protect from extreme pH
Sources
- Source dossier (provided)
Industry-knowledge claim — not yet pinned to a single primary source
Beauty drinks
- Positioning
- Inside-out skin elasticity (FFC where notified)
- Formulation notes
- Used by Astrim and other Aomori-affiliated brands; specific FFC claim wording must follow individual notifications
Joint-support supplements
- Positioning
- Joint comfort positioning, often combined with glucosamine or chondroitin in non-FFC products
- Formulation notes
- FFC notifications cite joint comfort endpoints in some cases — verify per brand
Looking for alternatives?
Common reasons buyers swap to a different ingredient — and what we'd suggest based on this ingredient's profile.
Vegan / plant-based alternatives
Salmon Nasal Cartilage Proteoglycan is animal-derived. If you need a non-animal source with similar functions, consider:
Fucoidan
フコイダン
INCI Fucoidan (from various brown seaweeds); MOQ from 1–10 kg.
Plant-based· shares 3 categories
Astaxanthin
アスタキサンチン
INCI Astaxanthin; FFC notification(s) on file; MOQ from 1–10 kg (oil-based concentrate).
Plant-based· shares 3 categories
Okinawa Mozuku Fucoidan
沖縄モズク由来フコイダン
Cladosiphon okamuranus Tokida source; INCI Cladosiphon Okamuranus Extract; FFC notification(s) on file; MOQ from 1-100 kg (powder, extract).
Plant-based· shares 3 categories
If you need to avoid fish
Salmon Nasal Cartilage Proteoglycan may contain fish. These ingredients offer comparable functions without it:
Fucoidan
フコイダン
INCI Fucoidan (from various brown seaweeds); MOQ from 1–10 kg.
fish-free· shares 3 categories
Astaxanthin
アスタキサンチン
INCI Astaxanthin; FFC notification(s) on file; MOQ from 1–10 kg (oil-based concentrate).
fish-free· shares 3 categories
Okinawa Mozuku Fucoidan
沖縄モズク由来フコイダン
Cladosiphon okamuranus Tokida source; INCI Cladosiphon Okamuranus Extract; FFC notification(s) on file; MOQ from 1-100 kg (powder, extract).
fish-free· shares 3 categories
More cost-efficient options
Salmon Nasal Cartilage Proteoglycan is positioned in the luxury tier. These ingredients offer similar functions at lower cost:
Astaxanthin
アスタキサンチン
INCI Astaxanthin; FFC notification(s) on file; MOQ from 1–10 kg (oil-based concentrate).
Cost-efficient· shares 3 categories
L-Theanine
L-テアニン
FFC notification(s) on file; MOQ from 1-100 kg (pharmaceutical-grade powder).
Cost-efficient· shares 3 categories
Galactomyces Ferment Filtrate
ガラクトミセス発酵濾液
INCI Galactomyces Ferment Filtrate; MOQ from 10–50 kg.
Cost-efficient· shares 2 categories
When does it make sense to swap an ingredient? Read the swap guide →
Japanese suppliers
Ichimaru Pharcos Co., Ltd.
一丸ファルコス株式会社
Motosu, GifuEst. 1959English supportExport experienceCOSMOSEcocertProteoglycan F (food grade) and Proteoglycan IPC (cosmetic grade)
Kakuhiro Co., Ltd.
株式会社角弘
Aomori City, AomoriAomori PG brand; mass-production pioneer since 2003
Astrim Co., Ltd.
株式会社アストリム
GifuProteoglycan F in FFC skin-elasticity supplements
DyDo DRINCO, Inc.
ダイドードリンコ株式会社
OsakaEnglish supportExport experienceHirosaki University co-research; proteoglycan + black ginger + raw coffee bean formulation
Ihara Fisheries Co., Ltd.
井原水産株式会社
HokkaidoPotential byproduct supply from Hokkaido salmon processing
Maruha Nichiro Corporation
マルハニチロ株式会社
Koto, TokyoEst. 1880English supportExport experienceFSSC 22000ISO 22000Marine-bioscience proteoglycan supply
Disclaimer
Japan Ingredient Sourcing Platform introduces overseas buyers to Japanese ingredient manufacturers. The platform is an information service only and is not a party to any purchase, supply, or manufacturing contract between buyer and seller.
Information shown — including company details, product descriptions, regions of origin, minimum order quantities, lead times, certifications, and regulatory references — is compiled primarily from publicly available sources and manufacturer websites. Specifications change without notice; buyers are expected to verify current specifications, pricing, certification status, and regulatory compliance directly with each manufacturer before placing orders or signing contracts.
The platform operator is not licensed to provide legal, regulatory, customs, tax, or professional advice. References to third-party companies, products, certifications, trademarks, and geographical indications (GI) are factual and do not imply endorsement, sponsorship, or affiliation. All trademarks are the property of their respective owners.
Last updated: 2026-04-24