Japan Ingredient Sourcing
Active component / 機能性成分Food ingredientsPhase 2 · 2a

Soy Isoflavones & Equol

大豆イソフラボン・エクオール (Daizu Isoflavone / Equol)

femcare-wellnessffc-accepted
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At a glance

Japanese name大豆イソフラボン・エクオール
RomajiDaizu Isoflavone / Equol
CategoryFood ingredients
Regions of originNationwide (Otsuka Pharmaceutical Tokushima facility)
Typical MOQ1 kg (concentrate) – 100 kg (lower-concentration grades)
Japan regulatory statusFFC-accepted for 'bone maintenance'; Tokuho approvals for legacy products
Suppliers listed5 suppliers

About this ingredient

Soy isoflavones (aglycone and glycoside forms) and S-Equol produced by Lactococcus 20-92 fermentation. Otsuka Pharmaceutical's 'Equelle' (2014) was the world's first commercial fermented-soy Equol supplement. Only ~50% of Japanese (~30% of Western) women naturally produce Equol from dietary soy.

Regulatory status

JapanFFC-accepted for 'bone maintenance'; Tokuho approvals for legacy products
EUNovel food framework applies for isolated isoflavones
United StatesDSHEA dietary supplement; FDA-notified claims available

Japanese suppliers

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Last updated: 2026-04-24