Supplements · Amino acids & peptides

Gamma-Aminobutyric Acid (GABA)

γ-アミノ酪酸 (Gamma amino rakusan)

Also known as: GABA

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At a glance

CategorySupplements
INCI nameAminobutyric Acid (cosmetic context)
Japanese labeling nameGABA / γ-アミノ酪酸
Common Japanese notationsGABA, γ-アミノ酪酸
CAS number56-12-2
OriginNaturally occurring (also produced by fermentation of plant substrates)
Typical functionsFunctional food ingredient (stress and sleep support), Cosmetic skin conditioning
Regulatory status in JapanMany Foods with Function Claims (機能性表示食品) notifications involving GABA are on file with the Consumer Affairs Agency. Cosmetic use under JSCI dictionary.

Gamma-aminobutyric acid (GABA) is a non-protein amino acid that functions as the principal inhibitory neurotransmitter in the central nervous system. In Japan, GABA is one of the most prominent functional food ingredients under the Foods with Function Claims system, with notifications around stress reduction, sleep quality, and blood pressure support.

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Classification

Tags below link to other ingredients sharing the same attribute, so you can pivot from one ingredient to its peers.

Common OEM product categories

Finished-product categories where Japanese OEM manufacturers commonly formulate with this ingredient.

  • FFC supplements (stress, sleep, blood pressure)
  • Functional chocolate and confectionery
  • Functional beverages
  • Functional rice products

Ingredient profile

GABA is a four-carbon amino acid produced both endogenously in animals and through bacterial / fermentation processes. Commercial GABA for supplement and food use is typically produced through Lactobacillus fermentation of glutamate-rich substrates.

OEM applications

In Japan, GABA appears in functional supplements, chocolate products, beverages, and rice products marketed under various Foods with Function Claims notifications.

Regulatory classification in Japan

Many FFC notifications involving GABA have been submitted to the Consumer Affairs Agency. Specific brand-claim combinations should be verified in the agency's notification database.

Regulatory classification in other markets

EUSupplement use of GABA in higher concentrations may be subject to Novel Food evaluation depending on the source.
USASold as a dietary supplement.
ChinaCosmetic uses subject to IECIC verification; supplement uses subject to specific authority review.
KoreaPermitted.

Market reference formulations

Example finished products are diverse across multiple product categories. Specific listings will be added after verification.

All brand names and product names referenced anywhere on this site are the property of their respective owners. Example entries are provided for informational purposes only and do not imply endorsement.

Alternative ingredients

Related ingredients commonly evaluated as substitutes.

Quick answers

What is Gamma-Aminobutyric Acid (GABA)?
Gamma-aminobutyric acid (GABA) is a non-protein amino acid that functions as the principal inhibitory neurotransmitter in the central nervous system. In Japan, GABA is one of the most prominent functional food ingredients under the Foods with Function Claims system, with notifications around stress reduction, sleep quality, and blood pressure support.
What is the regulatory status of Gamma-Aminobutyric Acid (GABA) in Japan?
Many Foods with Function Claims (機能性表示食品) notifications involving GABA are on file with the Consumer Affairs Agency. Cosmetic use under JSCI dictionary.
What products typically use Gamma-Aminobutyric Acid (GABA)?
FFC supplements (stress, sleep, blood pressure) / Functional chocolate and confectionery / Functional beverages / Functional rice products
Where does Gamma-Aminobutyric Acid (GABA) come from?
Naturally occurring (also produced by fermentation of plant substrates)
What is the INCI / JSCI labeling name for Gamma-Aminobutyric Acid (GABA)?
INCI: Aminobutyric Acid (cosmetic context) / JSCI: GABA / γ-アミノ酪酸

FAQ for OEM buyers

Q. What is GABA and how does it function in the body?

GABA (gamma-aminobutyric acid) is a non-protein amino acid that acts as the principal inhibitory neurotransmitter in the mammalian central nervous system. In food applications, it is consumed as a functional ingredient and is regulated as a food, not a drug.

Q. How is commercial GABA produced for food use in Japan?

Most food-grade GABA in Japan is produced by lactic acid bacteria fermentation of glutamate-rich substrates. Chemical synthesis routes also exist but are less common in functional food applications.

Sources

  • Pharmafoods Tea-Origin GABA technical material
  • Source dossier (provided)

Industry-knowledge claim — not yet pinned to a single primary source

Q. What endpoints are GABA Foods with Function Claims (FFC) typically notified for in Japan?

FFC notifications involving GABA in Japan have been submitted around endpoints including stress reduction, sleep quality, and blood pressure support. Specific brand/claim combinations should be verified in the Consumer Affairs Agency's notification database.

Q. What is the CAS number for GABA?

GABA has CAS number 56-12-2.

Q. How is GABA labeled in Japanese cosmetic ingredient lists?

In cosmetic contexts the JSCI labeling name is generally rendered as GABA / γ-アミノ酪酸; the INCI form Aminobutyric Acid is used in international filings.

Sources

  • JSCI cosmetic ingredient dictionary (industry reference)

Industry-knowledge claim — not yet pinned to a single primary source

Use cases

  • FFC stress and sleep supplements

    Positioning
    Daily stress reduction or sleep quality, notified under the Foods with Function Claims system
    Typical usage level
    Per individual FFC notification (commonly ~28–100 mg/day depending on endpoint)
    Formulation notes
    Commonly delivered as tablets or capsules; bitter/salty taste in direct beverage applications
  • Functional chocolate

    Positioning
    Stress-relief chocolate marketed under FFC
    Formulation notes
    Incorporated into chocolate matrix; actual claim wording must match the notified endpoint
  • Functional rice products

    Positioning
    GABA-enriched germinated brown rice for blood-pressure-support positioning
    Formulation notes
    GABA accumulates naturally during germination of brown rice; enriched lots are often blended with conventional rice

    Sources

    • Source dossier (provided)

    Industry-knowledge claim — not yet pinned to a single primary source

  • Functional beverages

    Positioning
    Relaxation or sleep support beverages
    Formulation notes
    Stable in low-pH beverages; flavor masking generally required at higher dosages

    Sources

    • Source dossier (provided)

    Industry-knowledge claim — not yet pinned to a single primary source

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Official regulatory databases

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References

  1. Japan Consumer Affairs Agency — Foods with Function Claims notification database

Last updated: 2026-04-22. Ingredient entries are reviewed at least annually against current regulatory listings.

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