Cosmetics · Quasi-drug actives

Hinokitiol

ヒノキチオール (Hinokitiōru)

Also known as: β-Thujaplicin

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At a glance

Category	Cosmetics
INCI name	Hinokitiol↗
Japanese labeling name	ヒノキチオール
Common Japanese notations	ヒノキチオール
CAS number	499-44-5↗
Origin	Plant-derived (naturally present in hiba [Thujopsis dolabrata] and hinoki [Chamaecyparis obtusa]); also produced synthetically.
Typical functions	Antimicrobial, Preservative support, Skin conditioning
Regulatory status in Japan	Cosmetic ingredient listed in the JSCI (Japanese Cosmetic Industry Association) labeling name dictionary. Hinokitiol has specific concentration-dependent considerations in some product categories.

Hinokitiol (β-thujaplicin) is a tropolone-family compound naturally present in hiba (Thujopsis dolabrata) and hinoki (Chamaecyparis obtusa) heartwood. Its isolation from these Japanese trees and subsequent use across cosmetic, oral-care, and scalp-care applications has made it a recognizable ingredient in Japanese-market product formulations.

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Classification

Tags below link to other ingredients sharing the same attribute, so you can pivot from one ingredient to its peers.

Product applications

Functions

Regulatory tags

Origin

Plant-derived319

Common OEM product categories

Finished-product categories where Japanese OEM manufacturers commonly formulate with this ingredient.

Scalp and hair care
Deodorant products
Specialty skincare
Oral care

Ingredient profile

Hinokitiol is the tropolone-family compound 2-hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one, present in varying proportions in several cypress-family species. Commercial isolation is primarily from hiba heartwood.

Both naturally sourced and synthetic hinokitiol are commercially available. Supply-chain documentation distinguishes the two; both are handled under the same INCI name.

OEM applications

In cosmetics, hinokitiol appears in scalp tonics, deodorant products, specialty skincare, and oral care. It is often a background-function ingredient that supports formulation stability in addition to its active-use positioning.

Regulatory classification in Japan

Cosmetic use is permitted under the JSCI dictionary. Concentration-dependent considerations apply in some product categories.

Regulatory classification in other markets

EU	Hinokitiol is listed in CosIng. Some restrictions may apply depending on product type and concentration; check current Cosmetics Regulation annexes.
USA	INCI recognized by PCPC.
China	Permitted per IECIC listings; verify concentration ranges.
Korea	Permitted under KFDA / MFDS.

Market reference formulations

Example finished products will be added after each product's current full ingredient list has been verified.

All brand names and product names referenced anywhere on this site are the property of their respective owners. Example entries are provided for informational purposes only and do not imply endorsement.

Typical OEM use levels

Formulation ranges per finished-product application. Verify against the cited source before production.

Application	Typical range	Regulatory limit	Notes
Cosmetic / scalp-care serum (Japan)	0.05–0.1%	—	Listed in Japan's positive list (化粧品基準); upper-limit may apply by product type(化粧品基準 (厚生労働省))

Stability & compatibility

pH range: pH 4–8
Temperature: Stable at standard cosmetic processing temperatures
Incompatibilities: Iron / copper ions (chelation causes discoloration)
Highly alkaline systems

Naturally chelates metals — strong color shift in presence of Fe/Cu. Sequester with EDTA / sodium phytate.

Storage requirements

How the receiving OEM facility needs to handle inbound raw material.

Temperature: Cool, ≤25°C
Conditions: Sealed; protect from prolonged light exposure
Shelf life: 24 months sealed

Takasago / supplier SDS

Supply concentration

Where this ingredient comes from — useful for single-source-risk planning.

Primary regions: Source: Taiwanese hinoki (Chamaecyparis taiwanensis) and Western red cedar; synthetic production also dominant
Import dependence: Domestic Japanese hinoki contains very little hinokitiol; commercial supply is imported from Taiwan or synthesized

Industrial chemistry references

Alternative ingredients

Related ingredients commonly evaluated as substitutes.

Quick answers

What is Hinokitiol?: Hinokitiol (β-thujaplicin) is a tropolone-family compound naturally present in hiba (Thujopsis dolabrata) and hinoki (Chamaecyparis obtusa) heartwood. Its isolation from these Japanese trees and subsequent use across cosmetic, oral-care, and scalp-care applications has made it a recognizable ingredient in Japanese-market product formulations.
What is the regulatory status of Hinokitiol in Japan?: Cosmetic ingredient listed in the JSCI (Japanese Cosmetic Industry Association) labeling name dictionary. Hinokitiol has specific concentration-dependent considerations in some product categories.
What products typically use Hinokitiol?: Scalp and hair care / Deodorant products / Specialty skincare / Oral care
Where does Hinokitiol come from?: Plant-derived (naturally present in hiba [Thujopsis dolabrata] and hinoki [Chamaecyparis obtusa]); also produced synthetically.
What is the INCI / JSCI labeling name for Hinokitiol?: INCI: Hinokitiol / JSCI: ヒノキチオール

Used in similar product applications

Other ingredients commonly used in the same finished-product families.

Sharing similar functions

Ingredients that overlap on functional benefit tags.

From the same origin

Other ingredients that share an origin classification.

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FAQ for OEM buyers

Q. What is the regulatory status of hinokitiol in cosmetics in major markets?

Hinokitiol is INCI-listed and accepted for cosmetic use in Japan, US, Korea, China, and Taiwan. EU regulatory status is more restrictive — hinokitiol is not listed in CosIng and has historically not been an approved cosmetic ingredient in the EU; check current EU SCCS status and Annex II (prohibited list) before EU-market launches.